Contact Information
M4523 SPH II
1415 Washington Heights
Ann Arbor, Michigan 48109-2029
Office: (734) 764-6742
E-mail: jianghui AT umich.edu
Professional Summary
Hui Jiang is a Professor in the Department
of Biostatistics at University of Michigan. He received his Ph.D. in Computational and
Mathematical Engineering from Stanford University. Before joining the University of Michigan,
he was a postdoctoral scholar in the Department of Statistics
and Genome Technology Center at Stanford University. He is interested in
developing statistical and computational methods for the analysis of
large-scale biological data generated using modern high-throughput
technologies.
Research Interests
- Statistical Genomics and Bioinformatics
- High-throughput genomics, sequencing data, RNA-Seq, gene expression, cancer genomics
- Computational Statistics
- Statistical computing, optimization, resampling, high-dimensional data, penalized models, variable selection, machine learning
Software & Programs
Selected Publications (Google Scholar)
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Tran L, Li G, Luo L, Jiang H (2024) A fast solution to the lasso problem with equality constraints Journal of Computational and Graphical Statistics, 33 (3): 804-813. [online][code]
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Shi Y, Shi W, Wang M, Lee J, Kang H, Jiang H (2023) Accurate and fast small p-value estimation for permutation tests in high-throughput genomic data analysis with the cross-entropy method Statistical Applications in Genetics and Molecular Biology, 22 (1). [online][arXiv][code]
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Zhai J, Jiang H (2023) Two-sample test with g-modeling and its applications Statistics in Medicine, 42 (1): 89-104. [online][code]
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Tran L, He K, Wang D, Jiang H (2023) A Cross-Validation Statistical Framework for Asymmetric Data Integration Biometrics, 79 (2): 1280-1292. [online][code]
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Zhai J, Ji H, Jiang H (2023) Reconstruction of Single-Cell Trajectories Using Stochastic Tree Search Genes, 14(2), 318. [online][code]
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Zhu Y, Shen X, Jiang H, Wong WH (2023) Collaborative multilabel classification Journal of the American Statistical Association, 118 (542): 913-924. [online]
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Shi Y, Lee J, Kang H, Jiang H (2022) A Two-part Mixed Model for Differential Expression Analysis in Single-cell High-throughput Gene Expression Data Genes, 13(2), 377. [online][code]
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Wu W, Taylor, JMG, Brouwer AF, Luo L, Kang J, Jiang H, He K (2022) Scalable Proximal Methods for Cause-Specific Hazard Modeling with Time-Varying Coefficients Lifetime Data Analysis, 28: 194-218. [online]
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Liu K, Shen L, Jiang H (2019) Joint Between-Sample Normalization and Differential Expression Detection through L0-regularized Regression BMC Bioinformatics, 20(Suppl 16): 593. [online][code]
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Shi Y, Wang M, Shi W, Lee J, Kang H, Jiang H (2019) Accurate and Efficient Estimation of Small P-values with the Cross-Entropy Method: Applications in Genomic Data Analysis Bioinformatics, 35 (14): 2441-2448. [online][arXiv][code]
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Liu K, Ye J, Yang Y, Shen L, Jiang H (2019) A Unified Model for Joint Normalization and Differential Gene Expression Detection in RNA-Seq data IEEE/ACM Transactions on Computational Biology and Bioinformatics, 16 (2): 442-454. [online][arXiv][code]
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Liu T, Jiang H (2019) Minimizing Sum of Truncated Convex Functions and its Applications Journal of Computational and Graphical Statistics, 28 (1): 1-10. [online][arXiv][code]
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Segal B, Elliott M, Braun T, Jiang H (2018) P-splines with an l1 penalty for repeated measures Electronic Journal of Statistics, 12 (2): 3554-3600. [online][arXiv][code]
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Segal B, Braun T, Elliott M, Jiang H (2018) Fast Approximation of Small p-values in Permutation Tests by Partitioning the Permutations Biometrics, 74 (1): 196-206. [online][arXiv][software][code]
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He K, Zhou X, Jiang H, Wen X, Li Y (2018) False discovery control for penalized variable selections with high-dimensional covariates Statistical Applications in Genetics and Molecular Biology, 17(6). [online]
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Zhao L, Wu W, Feng D, Jiang H, Nguyen X (2018) Bayesian Analysis of RNA-Seq Data Using a Family of Negative Binomial Models Bayesian Analysis, 13 (2): 411-436. [online]
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Jiang H, Zhan T (2017) Unit-Free and Robust Detection of Differential Expression from RNA-Seq Data Statistics in Biosciences, 9: 178-199. [online][arXiv][code]
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Jiang H, Mu JC, Yang K, Du C, Lu L, Wong WH (2016) Computational Aspects of Optional Polya Tree Journal of Computational and Graphical Statistics, 25 (1): 301-320. [online][arXiv][software]
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Shi Y, Chinnaiyan AM, Jiang H (2015) rSeqNP: A non-parametric approach for detecting differential expression and splicing from RNA-Seq data Bioinformatics, 31 (13): 2222-2224. [online][software]
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Jiang H, Salzman J (2015) A penalized likelihood approach for robust estimation of isoform expression Statistics and Its Interface, 8 (4): 437-445. [online][arXiv]
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Lu L, Jiang H, Wong WH (2013) Multivariate density estimation by Bayesian Sequential Partitioning Journal of the American Statistical Association, 108 (504): 1402-1410. [online]
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Shi Y, Jiang H (2013) rSeqDiff: Detecting differential isoform expression from RNA-Seq data using hierarchical likelihood ratio test PLoS One, 8 (11): e79448. [online][software]
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Jiang H, Salzman J (2012) Statistical properties of an early stopping rule for resampling-based multiple testing Biometrika, 99 (4): 973-980. [online]
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Mu JC, Jiang H, Kiani A, Mohiyuddin M, Asadi NB, Wong WH (2012) Fast and Accurate Read Alignment for Resequencing Bioinformatics, 28 (18): 2366-2373. [online][software]
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Salzman J, Jiang H, Wong WH (2011) Statistical Modeling of RNA-Seq Data Statistical Science, 26 (1): 62-83. [online][arXiv][technical report][software]
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Li J, Jiang H, Wong WH (2010) Modeling Non-Uniformity in Short-Read Rates in RNA-Seq Data Genome Biology, 11: R50. [online][software]
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Au KF, Jiang H, Lin L, Xing Y, Wong WH (2010) Detection of Splice Junctions from Paired-End RNA-Seq Data by SpliceMap Nucleic Acids Research, 38 (14): 4570-4578. [online][software]
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Jiang H, Wang F, Dyer NP, Wong WH (2010) CisGenome Browser: A flexible tool for genomic data visualization Bioinformatics, 26 (14): 1781–1782. [online][software]
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Jiang H, Wong WH (2009) Statistical Inferences for Isoform Expression in RNA-Seq Bioinformatics, 25 (8): 1026–1032. [online][preprint][software]
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Hiller D, Jiang H, Xu W, Wong WH (2009) Identifiability of Isoform Deconvolution from Junction Arrays and RNA-Seq Bioinformatics, 25 (23): 3056-3059. [online]
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Kapur K, Jiang H, Xing Y, Wong WH (2008) Cross-Hybridization Modeling on Affymetrix Exon Arrays Bioinformatics, 24 (24): 2887-2893. [online]
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Jiang H, Wong WH (2008) SeqMap: Mapping Massive Amount of Oligonucleotides to the Genome Bioinformatics, 24 (20). [online][software]
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Ji H, Jiang H, Ma W, Johnson D, Myers R, Wong WH (2008) An Integrated Software System for Analyzing ChIP-chip and ChIP-seq Data Nature Biotechnology, 26: 1293-1300. [online][software]
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Jiang H, Liu Y, Su Z (2008) Optimizing Chemotherapy Scheduling by Iteratively Solving a Recurrence Equation Algorithmic Operations Research, 3(2). [online]
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